Quality you Can Trust

Every batch is independently tested by an ISO/IEC 17025:2017 accredited laboratory.
Includes COA with every order.

Melanotan I (MT-1)

Name: Melanotan I (MT-1)
Brand: Rx Peptides Co.
Availability: InStock

Size

$37.00

3RD Party Tested

COA Verified

High Purity

99% + Purity

Fast Fulfillment

Fast & Reliable

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Ships within 24 hours

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Key Benefits

Research Use Only

Certified purity. Consistent performance. Every batch

High-affinity peptides designed for targeted discover

Consistently top-rated for purity and batch-to-batch stability

High purity lyophilized powder

For laboratory research purpose only

SKU RX-MT-1-M-146 Category Peptides

Quality you Can Trust

Every batch is independently tested by an ISO/IEC 17025:2017 accredited laboratory.
Includes COA with every order.

These products are intended for laboratory research purposes only, and are not for human or animal consumption. The products are not intended to diagnose, treat, cure, or prevent any disease. The products should not be used as a food, drug, cosmetic, or other household use.

Description

Melanotan I is a melanocortin receptor agonist that mimics the activity of endogenous α-MSH, a peptide hormone involved in pigmentation and melanocyte signaling pathways.

In research environments, MT-1 is studied for:

Activation of MC1R receptors
Regulation of melanogenesis pathways
Cellular pigmentation response mechanisms
Melanocyte signaling and skin biology models (preclinical research)

Unlike Melanotan II, MT-1 is more selective toward MC1R pathways, making it a key molecule in pigmentation-focused research models.

Key Scientific Features

α-MSH analog peptide (melanocortin system)
High-purity research-grade formulation
Selective MC1R receptor activity (research context)
HPLC/MS verified identity (batch dependent)
Lyophilized for stability and storage
Full Certificate of Analysis (COA) included
Manufactured under controlled laboratory conditions

Research Applications (Non-Therapeutic)

Based on published scientific literature — not intended as medical or cosmetic claims.

Melanotan I is used in research involving:

Melanocortin receptor signaling pathways
Melanin synthesis (melanogenesis) studies
Pigmentation biology and melanocyte function models
MC1R receptor activation mechanisms
Skin cell signaling pathway research (preclinical models)
Photobiology and UV-response pathway studies in controlled systems

Scientific Evidence & References

Melanotan I has been studied in dermatological and receptor biology research:

MC1R Melanocortin Receptor Biology Overview (NCBI)
Alpha-MSH and Melanogenesis Pathways Review
Clinical and Experimental Use of Afamelanotide (MT-1 analog)

These sources describe melanocortin receptor activation and pigmentation signaling mechanisms relevant to MT-1 research.

Mechanism of Action

In laboratory models, Melanotan I functions through:

Binding to MC1R (melanocortin 1 receptor)
Activation of intracellular signaling pathways (cAMP-mediated pathways)
Regulation of melanocyte activity and melanin synthesis pathways
Modulation of pigmentation-related gene expression in experimental systems

Handling & Storage

Melanotan I is supplied as a lyophilized peptide powder requiring careful handling:

Store at 2–8°C
Protect from light, heat, and moisture
Avoid repeated freeze-thaw cycles
Reconstitute only under controlled laboratory conditions

Why Researchers Choose Melanotan I

Selective MC1R receptor agonist
Widely used in pigmentation biology research
Strong melanocortin system relevance
High analytical purity and batch consistency
Supported by extensive receptor biology literature
Full COA and traceability provided

Important Notice

For Research Use Only. Not for human or veterinary use.
This product is not a drug, cosmetic, or therapeutic agent. It is intended strictly for laboratory research and analytical applications.

FAQ's

Research Use Only / Not for Human Consumption

These products are intended for laboratory research purposes only, and are not for human or animal consumption. The products are not intended to diagnose, treat, cure, or prevent any disease. The products should not be used as a food, drug, cosmetic, or other household use. By accessing this website or purchasing from this website, you agree that that it is your sole responsibility to ensure compliance with applicable laws and regulations within your jurisdiction; and you understand and acknowledge that no information on this website should be construed as medical advice.

Product Testing

We verify every batch of every product through accredited, independent third-party laboratories. Since each product requires unique analytical methods and equipment, we collaborate with specialized laboratories and PhDs in analytical and organic chemistry to design our testing protocols.

Analytical techniques we utilize include: NMR, FTIR, HPLC, LC-MS, GC-MS, TLC, ICP-MS, Gravimetry, UV-Vis, Titration, Melting Point, and Organoleptics.
We primarily test for purity, content, sterility, and endotoxins (LPS).

Product Appearance Variations

Variations in color, texture, odor or even biochemical properties may occur due to polymorphy (differences in crystal structure).These variations do not compromise product quality.

Peptide Form

Our peptides are provided in lyophilized powder form to ensure maximum stability. In any other format, peptide integrity would rapidly degrade before reaching the customer.

Optimal storage: Below –20 °C.
Short-term storage: Refrigeration at 4 °C for up to 2 years.
Room temperature tolerance: 4–6 weeks with minimal degradation if protected from direct sunlight (suitable for international shipping).

Peptide Top Colors

Images on our site display white tops for illustration purposes only. In practice, vial tops may vary in color to help our staff distinguish products during processing.

Peptide Powder Appearance

Lyophilized peptides typically form a solid cake. However, during transit, the cake may break or appear uneven. This is an aesthetic issue only and does not impact quality, potency, or purity.

Some peptides and proteins may appear larger due to buffering requirements. This is normal.

Storage Instructions

Storage instructions are provided on each product listing and product label.

General storage: Store in a cool, dry place away from heat, moisture, and sunlight.
Best practice: Refrigeration or freezing is recommended for long-term stability.

Solution Flakes, Precipitation, and Separation

Solution-based products may occasionally:

Crystallize (form flakes)
Precipitate (fall out of suspension)
Separate (form layers)
Lose homogeneity

This typically occurs during cold transit or accidental freezing. To restore uniformity:

Warm the vial in 50–70 °C water for 5–10 minutes.
Shake vigorously to re-suspend.

If the product does not return to homogeneity, please contact us.

Extreme Temperature Exposure

All molecules degrade over time, but proper storage significantly slows this process.

Low temperature exposure: Generally safe; may cause precipitation in solutions but does not accelerate degradation.
High temperature exposure: Prolonged exposure may accelerate degradation.
- Example: A product requiring room temperature storage exposed to 115 °F for a few days will not show measurable degradation once properly stored again.
Cold-storage products (–20 °C): Short-term exposure (<24h) to ambient temperatures does not significantly degrade the product unless oxygen, moisture, or sunlight are also present.

Accidental Exposure or Ingestion

Contact your local toxicologist. United States: Poison Help Line — 1-800-222-1222
Seek immediate medical attention.
Always handle products using proper PPE.
Refer to the product’s SDS for safety guidelines.